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GALE 抗体 (N-Term)

The 兔 多克隆 anti-GALE antibody is suitable to detect GALE in samples from 人. It has been validated for WB.
产品编号 ABIN631451
发货至: 中国
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Quick Overview for GALE 抗体 (N-Term) (ABIN631451)

抗原

See all GALE 抗体
GALE (UDP-Galactose-4-Epimerase (GALE))

适用

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宿主

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克隆类型

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多克隆

标记

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This GALE antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    GALE antibody was raised against the N terminal of GALE

    纯化方法

    Affinity purified

    免疫原

    GALE antibody was raised using the N terminal of GALE corresponding to a region with amino acids AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRR
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    GALE Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this GALE antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GALE antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    GALE (UDP-Galactose-4-Epimerase (GALE))

    别名

    GALE

    背景

    GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation.

    分子量

    38 kDa (MW of target protein)

    途径

    Response to Water Deprivation, Cellular Glucan Metabolic Process
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