GALE 抗体 (N-Term)
Quick Overview for GALE 抗体 (N-Term) (ABIN631451)
抗原
See all GALE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- GALE antibody was raised against the N terminal of GALE
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纯化方法
- Affinity purified
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免疫原
- GALE antibody was raised using the N terminal of GALE corresponding to a region with amino acids AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRR
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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GALE Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this GALE antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GALE antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- GALE (UDP-Galactose-4-Epimerase (GALE))
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别名
- GALE
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背景
- GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation.
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分子量
- 38 kDa (MW of target protein)
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途径
- Response to Water Deprivation, Cellular Glucan Metabolic Process
抗原
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