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TYMS 抗体 (C-Term)

This anti-TYMS antibody is a 兔 多克隆 antibody detecting TYMS in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN631290
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TYMS 抗体 (C-Term) (ABIN631290)

抗原

See all TYMS 抗体
TYMS (Thymidylate Synthetase (TYMS))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TYMS antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    TYMS antibody was raised against the C terminal of TYMS

    纯化方法

    Affinity purified

    免疫原

    TYMS antibody was raised using the C terminal of TYMS corresponding to a region with amino acids HIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKME
  • 应用备注

    WB: 0.25 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    TYMS Blocking Peptide, (ABIN939139), is also available for use as a blocking control in assays to test for specificity of this TYMS antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TYMS antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    TYMS (Thymidylate Synthetase (TYMS))

    别名

    TYMS

    背景

    TYMS catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.

    分子量

    36 kDa (MW of target protein)

    途径

    Mitotic G1-G1/S Phases
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