PRAME 抗体 (N-Term)
Quick Overview for PRAME 抗体 (N-Term) (ABIN631203)
抗原
See all PRAME 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- PRAME antibody was raised against the N terminal of PRAME
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纯化方法
- Affinity purified
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免疫原
- PRAME antibody was raised using the N terminal of PRAME corresponding to a region with amino acids MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPR
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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PRAME Blocking Peptide, (ABIN5615531), is also available for use as a blocking control in assays to test for specificity of this PRAME antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PRAME antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
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别名
- PRAME
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背景
- PRAME functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. PRAME prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
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分子量
- 56 kDa (MW of target protein)
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途径
- Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
抗原
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