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HAAO 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects HAAO in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN631165
发货至: 中国
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Quick Overview for HAAO 抗体 (N-Term) (ABIN631165)

抗原

See all HAAO 抗体
HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))

适用

  • 22
  • 16
  • 9
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 30
  • 1

克隆类型

  • 30
  • 1
多克隆

标记

  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HAAO antibody is un-conjugated

应用范围

  • 26
  • 13
  • 13
  • 13
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    HAAO antibody was raised against the N terminal of HAAO

    纯化方法

    Affinity purified

    免疫原

    HAAO antibody was raised using the N terminal of HAAO corresponding to a region with amino acids HRDVVIRQGEIFLLPARVPHSPQRFANTVGLVVERRRLETELDGLRYYVG
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    HAAO Blocking Peptide, (ABIN939222), is also available for use as a blocking control in assays to test for specificity of this HAAO antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HAAO antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))

    别名

    HAAO

    背景

    3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders.

    分子量

    32 kDa (MW of target protein)
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