HAAO 抗体 (N-Term)
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Quick Overview for HAAO 抗体 (N-Term) (ABIN631165)
抗原
See all HAAO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- HAAO antibody was raised against the N terminal of HAAO
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纯化方法
- Affinity purified
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免疫原
- HAAO antibody was raised using the N terminal of HAAO corresponding to a region with amino acids HRDVVIRQGEIFLLPARVPHSPQRFANTVGLVVERRRLETELDGLRYYVG
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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HAAO Blocking Peptide, (ABIN939222), is also available for use as a blocking control in assays to test for specificity of this HAAO antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HAAO antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
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别名
- HAAO
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背景
- 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders.
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分子量
- 32 kDa (MW of target protein)
抗原
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