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HAX1 抗体 (Middle Region)

The 兔 多克隆 anti-HAX1 antibody (ABIN631119) specifically detects HAX1 in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN631119
发货至: 中国
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Quick Overview for HAX1 抗体 (Middle Region) (ABIN631119)

抗原

See all HAX1 抗体
HAX1 (HCLS1 Associated Protein X-1 (HAX1))

适用

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人, 小鼠

宿主

  • 55
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克隆类型

  • 57
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多克隆

标记

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This HAX1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    特异性

    HAX1 antibody was raised against the middle region of HAX1

    纯化方法

    Affinity purified

    免疫原

    HAX1 antibody was raised using the middle region of HAX1 corresponding to a region with amino acids LPGPESETPGERLREGQTLRDSMLKYPDSHQPRIFGGVLESDARSESPQP
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    HAX1 Blocking Peptide, (ABIN5613936), is also available for use as a blocking control in assays to test for specificity of this HAX1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HAX1 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    HAX1 (HCLS1 Associated Protein X-1 (HAX1))

    别名

    HAX1

    背景

    HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease.

    分子量

    31 kDa (MW of target protein)

    途径

    Regulation of Actin Filament Polymerization
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