Prohibitin 2 抗体 (C-Term)
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- 抗原 See all Prohibitin 2 (PHB2) 抗体
- Prohibitin 2 (PHB2)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Prohibitin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Prohibitin 2 antibody was raised against the C terminal of PHB2
- 纯化方法
- Affinity purified
- 免疫原
- Prohibitin 2 antibody was raised using the C terminal of PHB2 corresponding to a region with amino acids KLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
- Top Product
- Discover our top product PHB2 Primary Antibody
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- 应用备注
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WB: 0.5 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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Prohibitin 2 Blocking Peptide, catalog no. 33R-4533, is also available for use as a blocking control in assays to test for specificity of this Prohibitin 2 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PHB2 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- Prohibitin 2 (PHB2)
- 别名
- Prohibitin 2 (PHB2 产品)
- 背景
- PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.
- 分子量
- 33 kDa (MW of target protein)
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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