Adenylate Kinase 1 抗体 (Middle Region)
Quick Overview for Adenylate Kinase 1 抗体 (Middle Region) (ABIN630970)
抗原
See all Adenylate Kinase 1 (AK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- AK1 antibody was raised against the middle region of AK1
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纯化方法
- Affinity purified
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免疫原
- AK1 antibody was raised using the middle region of AK1 corresponding to a region with amino acids RIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKAT
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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AK1 Blocking Peptide, (ABIN5611982), is also available for use as a blocking control in assays to test for specificity of this AK1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of AK1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Adenylate Kinase 1 (AK1)
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别名
- AK1
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背景
- Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
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分子量
- 22 kDa (MW of target protein)
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途径
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
抗原
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