CAMLG 抗体 (N-Term)
Quick Overview for CAMLG 抗体 (N-Term) (ABIN630925)
抗原
See all CAMLG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- CAMLG antibody was raised against the N terminal of CAMLG
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纯化方法
- Affinity purified
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免疫原
- CAMLG antibody was raised using the N terminal of CAMLG corresponding to a region with amino acids LLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRV
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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CAMLG Blocking Peptide, (ABIN5612597), is also available for use as a blocking control in assays to test for specificity of this CAMLG antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CAMLG antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- CAMLG (Calcium Modulating Ligand (CAMLG))
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别名
- CAMLG
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背景
- The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
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分子量
- 33 kDa (MW of target protein)
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途径
- EGFR Signaling Pathway
抗原
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