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CAMLG 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects CAMLG in WB. It exhibits reactivity toward 人.
产品编号 ABIN630925
发货至: 中国
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Quick Overview for CAMLG 抗体 (N-Term) (ABIN630925)

抗原

See all CAMLG 抗体
CAMLG (Calcium Modulating Ligand (CAMLG))

适用

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宿主

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克隆类型

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多克隆

标记

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This CAMLG antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    CAMLG antibody was raised against the N terminal of CAMLG

    纯化方法

    Affinity purified

    免疫原

    CAMLG antibody was raised using the N terminal of CAMLG corresponding to a region with amino acids LLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRV
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    CAMLG Blocking Peptide, (ABIN5612597), is also available for use as a blocking control in assays to test for specificity of this CAMLG antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CAMLG antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    CAMLG (Calcium Modulating Ligand (CAMLG))

    别名

    CAMLG

    背景

    The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

    分子量

    33 kDa (MW of target protein)

    途径

    EGFR Signaling Pathway
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