Dynamin 1 抗体 (Middle Region)
Quick Overview for Dynamin 1 抗体 (Middle Region) (ABIN630914)
抗原
See all Dynamin 1 (DNM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- Dynamin 1 antibody was raised against the middle region of DNM1
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纯化方法
- Affinity purified
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免疫原
- Dynamin 1 antibody was raised using the middle region of DNM1 corresponding to a region with amino acids PPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPA
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Dynamin 1 Blocking Peptide, (ABIN5613275), is also available for use as a blocking control in assays to test for specificity of this Dynamin 1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DNM1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Dynamin 1 (DNM1)
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别名
- Dynamin 1
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背景
- DNM1 is a member of the dynamin subfamily of GTP-binding proteins. The protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
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分子量
- 95 kDa (MW of target protein)
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途径
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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