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HSPB8 抗体 (N-Term)

This anti-HSPB8 antibody is a 兔 多克隆 antibody detecting HSPB8 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN630901
发货至: 中国

Quick Overview for HSPB8 抗体 (N-Term) (ABIN630901)

抗原

See all HSPB8 抗体
HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

适用

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  • 1
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人, 小鼠, 大鼠

宿主

  • 76
  • 19
  • 1

克隆类型

  • 71
  • 25
多克隆

标记

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  • 1
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  • 1
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  • 1
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  • 1
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This HSPB8 antibody is un-conjugated

应用范围

  • 74
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  • 8
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Western Blotting (WB)
  • 抗原表位

    • 22
    • 15
    • 3
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    • 1
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    N-Term

    特异性

    HSPB8 antibody was raised against the N terminal of HSPB8

    纯化方法

    Affinity purified

    免疫原

    HSPB8 antibody was raised using the N terminal of HSPB8 corresponding to a region with amino acids ADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDW
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    HSPB8 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this HSPB8 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HSPB8 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

    别名

    HSPB8

    背景

    HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

    分子量

    21 kDa (MW of target protein)
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