HSPB8 抗体 (N-Term)
Quick Overview for HSPB8 抗体 (N-Term) (ABIN630901)
抗原
See all HSPB8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- HSPB8 antibody was raised against the N terminal of HSPB8
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纯化方法
- Affinity purified
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免疫原
- HSPB8 antibody was raised using the N terminal of HSPB8 corresponding to a region with amino acids ADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDW
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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HSPB8 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this HSPB8 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HSPB8 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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别名
- HSPB8
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背景
- HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
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分子量
- 21 kDa (MW of target protein)
抗原
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