TNKS1BP1 抗体 (Middle Region)
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北京 101111
Quick Overview for TNKS1BP1 抗体 (Middle Region) (ABIN630864)
抗原
See all TNKS1BP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- TNKS1 BP1 antibody was raised against the middle region of TNKS1 P1
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纯化方法
- Affinity purified
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免疫原
- TNKS1 BP1 antibody was raised using the middle region of TNKS1 P1 corresponding to a region with amino acids DGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFIE
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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TNKS1BP1 Blocking Peptide, (ABIN937331), is also available for use as a blocking control in assays to test for specificity of this TNKS1BP1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TNKS0 P1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
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别名
- TNKS1BP1
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背景
- TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.
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分子量
- 190 kDa (MW of target protein)
抗原
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