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TGIF1 抗体 (C-Term)

The 兔 多克隆 anti-TGIF1 antibody (ABIN630855) specifically detects TGIF1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN630855
发货至: 中国
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Quick Overview for TGIF1 抗体 (C-Term) (ABIN630855)

抗原

See all TGIF1 抗体
TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TGIF1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    TGIF1 antibody was raised against the C terminal of TGIF1

    纯化方法

    Affinity purified

    免疫原

    TGIF1 antibody was raised using the C terminal of TGIF1 corresponding to a region with amino acids GQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQSGLFNTPPPTPPDLN
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    TGIF1 Blocking Peptide, (ABIN938892), is also available for use as a blocking control in assays to test for specificity of this TGIF1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TGIF1 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

    别名

    TGIF1

    背景

    TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.

    分子量

    43 kDa (MW of target protein)

    途径

    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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