ALDOB 抗体 (Middle Region)
Quick Overview for ALDOB 抗体 (Middle Region) (ABIN630782)
抗原
See all ALDOB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- ALDOB antibody was raised against the middle region of ALDOB
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纯化方法
- Affinity purified
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免疫原
- ALDOB antibody was raised using the middle region of ALDOB corresponding to a region with amino acids KLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQ
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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ALDOB Blocking Peptide, (ABIN939889), is also available for use as a blocking control in assays to test for specificity of this ALDOB antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ALDOB antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
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别名
- ALDOB
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背景
- Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
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分子量
- 39 kDa (MW of target protein)
抗原
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