IMPDH2 抗体
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北京 101111
Quick Overview for IMPDH2 抗体 (ABIN630710)
抗原
See all IMPDH2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purified
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免疫原
- IMPDH2 antibody was raised using a synthetic peptide corresponding to a region with amino acids SCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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IMPDH2 Blocking Peptide, (ABIN5614190), is also available for use as a blocking control in assays to test for specificity of this IMPDH2 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IMPDH2 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
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别名
- IMPDH2
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背景
- IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
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分子量
- 56 kDa (MW of target protein)
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途径
- Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
抗原
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