PARP11 抗体
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- 抗原 See all PARP11 products
- PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PARP11 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purified
- 免疫原
- PARP11 antibody was raised using a synthetic peptide corresponding to a region with amino acids IKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKD
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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PARP11 Blocking Peptide, catalog no. 33R-4020, is also available for use as a blocking control in assays to test for specificity of this PARP11 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PARP11 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
- 别名
- PARP11 (PARP11 产品)
- 背景
- PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
- 分子量
- 39 kDa (MW of target protein)
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