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ING3 抗体 (N-Term)

This anti-ING3 antibody is a 兔 多克隆 antibody detecting ING3 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN630670
发货至: 中国

Quick Overview for ING3 抗体 (N-Term) (ABIN630670)

抗原

See all ING3 抗体
ING3 (Inhibitor of Growth Family, Member 3 (ING3))

适用

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人, 小鼠, 大鼠

宿主

  • 27
  • 4
  • 1

克隆类型

  • 29
  • 3
多克隆

标记

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This ING3 antibody is un-conjugated

应用范围

  • 21
  • 15
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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    ING3 antibody was raised against the N terminal of ING3

    纯化方法

    Affinity purified

    免疫原

    ING3 antibody was raised using the N terminal of ING3 corresponding to a region with amino acids MDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADEKVQLANQ
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    ING3 Blocking Peptide, (ABIN5614195), is also available for use as a blocking control in assays to test for specificity of this ING3 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ING3 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    ING3 (Inhibitor of Growth Family, Member 3 (ING3))

    别名

    ING3

    背景

    ING3 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers.

    分子量

    47 kDa (MW of target protein)
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