KPNA6 抗体
Quick Overview for KPNA6 抗体 (ABIN630643)
抗原
See all KPNA6 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purified
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免疫原
- Karyopherin Alpha 6 antibody was raised using a synthetic peptide corresponding to a region with amino acids STTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTP
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Karyopherin Alpha 6 Blocking Peptide, (ABIN5614255), is also available for use as a blocking control in assays to test for specificity of this Karyopherin Alpha 6 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KPNA6 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
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别名
- Karyopherin alpha 6
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背景
- The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. KPNA6 is a member of the importin alpha family.
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分子量
- 60 kDa (MW of target protein)
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途径
- Protein targeting to Nucleus
抗原
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