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TXNIP 抗体 (C-Term)

TXNIP 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN630604
发货至: 中国
  • 抗原 See all TXNIP 抗体
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    抗原表位
    • 16
    • 14
    • 9
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 63
    • 47
    • 32
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 72
    • 5
    克隆类型
    • 63
    • 14
    多克隆
    标记
    • 32
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXNIP antibody is un-conjugated
    应用范围
    • 59
    • 32
    • 16
    • 14
    • 14
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    特异性
    TXNIP antibody was raised against the C terminal of TXNIP
    纯化方法
    Affinity purified
    免疫原
    TXNIP antibody was raised using the C terminal of TXNIP corresponding to a region with amino acids DTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPP
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    Discover our top product TXNIP Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    TXNIP Blocking Peptide, catalog no. 33R-2201, is also available for use as a blocking control in assays to test for specificity of this TXNIP antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TXNIP antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    别名
    TXNIP (TXNIP 产品)
    别名
    EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody, Gm348 antibody, Trf3 antibody, TBP2 antibody, TRF3 antibody, 1200008J08Rik antibody, AA682105 antibody, Hyplip1 antibody, Tbp-2 antibody, Vdup1 antibody, sb:cb368 antibody, txnip antibody, thioredoxin interacting protein antibody, TATA box binding protein like 2 antibody, TATA-box binding protein like 2 antibody, thioredoxin interacting protein L homeolog antibody, thioredoxin interacting protein a antibody, TXNIP antibody, Tbpl2 antibody, TBPL2 antibody, Txnip antibody, txnip.L antibody, txnip antibody, txnipa antibody
    背景
    TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
    分子量
    44 kDa (MW of target protein)
    途径
    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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