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TXNIP 抗体 (C-Term)

This anti-TXNIP antibody is a 兔 多克隆 antibody detecting TXNIP in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN630604
发货至: 中国

Quick Overview for TXNIP 抗体 (C-Term) (ABIN630604)

抗原

See all TXNIP 抗体
TXNIP (Thioredoxin Interacting Protein (TXNIP))

适用

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  • 50
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  • 1
人, 小鼠, 大鼠

宿主

  • 74
  • 6

克隆类型

  • 65
  • 15
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
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  • 1
This TXNIP antibody is un-conjugated

应用范围

  • 56
  • 29
  • 18
  • 14
  • 14
  • 9
  • 8
  • 8
  • 5
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 16
    • 9
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    • 5
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    • 1
    • 1
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    • 1
    • 1
    • 1
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    C-Term

    特异性

    TXNIP antibody was raised against the C terminal of TXNIP

    纯化方法

    Affinity purified

    免疫原

    TXNIP antibody was raised using the C terminal of TXNIP corresponding to a region with amino acids DTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPP
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    TXNIP Blocking Peptide, (ABIN937587), is also available for use as a blocking control in assays to test for specificity of this TXNIP antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TXNIP antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    TXNIP (Thioredoxin Interacting Protein (TXNIP))

    别名

    TXNIP

    背景

    TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.

    分子量

    44 kDa (MW of target protein)

    途径

    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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