DLC1 抗体 (C-Term)
Quick Overview for DLC1 抗体 (C-Term) (ABIN630519)
抗原
See all DLC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- DLC1 antibody was raised against the C terminal of DLC1
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纯化方法
- Affinity purified
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免疫原
- DLC1 antibody was raised using the C terminal of DLC1 corresponding to a region with amino acids NLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGL
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应用备注
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WB: 0.5 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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DLC1 Blocking Peptide, (ABIN5613215), is also available for use as a blocking control in assays to test for specificity of this DLC1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DLC1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- DLC1 (Deleted in Liver Cancer 1 (DLC1))
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别名
- DLC1
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背景
- This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.
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分子量
- 52 kDa (MW of target protein)
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途径
- Tube Formation, Positive Regulation of Endopeptidase Activity
抗原
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