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IL-10RA 抗体 (N-Term)

This anti-IL-10RA antibody is a 兔 多克隆 antibody detecting IL-10RA in WB. Suitable for 人.
产品编号 ABIN630438
发货至: 中国

Quick Overview for IL-10RA 抗体 (N-Term) (ABIN630438)

抗原

See all IL-10RA (IL10RA) 抗体
IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL-10RA antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    IL10 R Alpha antibody was raised against the N terminal of IL10 A

    纯化方法

    Purified

    免疫原

    IL10 R Alpha antibody was raised using the N terminal of IL10 A corresponding to a region with amino acids GSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGN
  • 应用备注

    WB: 5 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    IL10R Alpha Blocking Peptide, (ABIN938981), is also available for use as a blocking control in assays to test for specificity of this IL10R Alpha antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IL10 A antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

    别名

    IL10R alpha

    背景

    IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.

    分子量

    61 kDa (MW of target protein)

    途径

    Growth Factor Binding
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