NrCAM 抗体 (N-Term)
Quick Overview for NrCAM 抗体 (N-Term) (ABIN630314)
抗原
See all NrCAM (NRCAM) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- NRCAM antibody was raised against the N terminal of NRCAM
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纯化方法
- Purified
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免疫原
- NRCAM antibody was raised using the N terminal of NRCAM corresponding to a region with amino acids NLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP
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应用备注
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WB: 2.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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NRCAM Blocking Peptide, catalog no. 33R-6774, is also available for use as a blocking control in assays to test for specificity of this NRCAM antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NRCAM antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))
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别名
- NRCAM
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背景
- Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. NRCAM is a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM may also play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of its gene have been associated with autism and addiction vulnerability.
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分子量
- 141 kDa (MW of target protein)
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途径
- Regulation of Cell Size
抗原
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