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P-Cadherin 抗体

The 兔 多克隆 anti-P-Cadherin antibody is suitable to detect P-Cadherin in samples from 人 和 小鼠. It has been validated for WB 和 IHC.
产品编号 ABIN630281
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for P-Cadherin 抗体 (ABIN630281)

抗原

See all P-Cadherin (CDH3) 抗体
P-Cadherin (CDH3)

适用

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人, 小鼠

宿主

  • 100
  • 33
  • 6
  • 2

克隆类型

  • 98
  • 38
  • 3
多克隆

标记

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This P-Cadherin antibody is un-conjugated

应用范围

  • 101
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Purified

    免疫原

    CDH3 antibody was raised using a synthetic peptide corresponding to a region with amino acids AVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQ
  • 应用备注

    WB: 1.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    CDH3 Blocking Peptide, (ABIN937001), is also available for use as a blocking control in assays to test for specificity of this CDH3 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CDH3 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    P-Cadherin (CDH3)

    别名

    CDH3

    背景

    CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

    分子量

    91 kDa (MW of target protein)
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