PCMT1 抗体
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北京 101111
Quick Overview for PCMT1 抗体 (ABIN630131)
抗原
See all PCMT1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- PCMT1 antibody was raised using a synthetic peptide corresponding to a region with amino acids APYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQD
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应用备注
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WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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PCMT1 Blocking Peptide, (ABIN936828), is also available for use as a blocking control in assays to test for specificity of this PCMT1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PCMT1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
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别名
- PCMT1
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背景
- Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
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分子量
- 25 kDa (MW of target protein)
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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