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- 抗原 See all CHRNB2 抗体
- CHRNB2 (Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHRNB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Purified
- 免疫原
- CHRNB2 antibody was raised using a synthetic peptide corresponding to a region with amino acids CKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWD
- Top Product
- Discover our top product CHRNB2 Primary Antibody
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anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 26-233) antibody
CHRNB2 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 2D12A2 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 86-244) antibodyCHRNB2 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 322-458) antibodyCHRNB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 26-130) antibodyCHRNB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 155-204) antibodyCHRNB2 适用: 人, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (Internal Region) antibodyVerified CHRNB2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 21-70) antibodyCHRNB2 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 豚鼠, 斑马鱼, Bat, 猴, 非洲爪蟾, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 66-100) antibodyCHRNB2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB53583 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) antibodyCHRNB2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) antibodyCHRNB2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 2.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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CHRNB2 Blocking Peptide, catalog no. 33R-1722, is also available for use as a blocking control in assays to test for specificity of this CHRNB2 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CHRNB2 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- CHRNB2 (Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))
- 别名
- CHRNB2 (CHRNB2 产品)
- 别名
- EFNL3 antibody, nAChRB2 antibody, NACHRB2 antibody, Acrb-2 antibody, Acrb2 antibody, C030030P04Rik antibody, [b]2-nAchR antibody, cholinergic receptor nicotinic beta 2 subunit antibody, cholinergic receptor nicotinic beta 2 subunit S homeolog antibody, cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) antibody, CHRNB2 antibody, chrnb2.S antibody, Chrnb2 antibody
- 背景
- Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy . Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3), outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M, which occurred de novo in twins, markedly increases the receptor's sensitivity to acetylcholine. Phenotypically, the mutation is associated not only with typical ADNFLE, but also with distinct deficits in memory. The cognitive problems are most obvious in tasks requiring the organization and storage of verbal information.
- 分子量
- 57 kDa (MW of target protein)
- 途径
- Sensory Perception of Sound, Feeding Behaviour
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