Ube2t 抗体
Quick Overview for Ube2t 抗体 (ABIN6298352)
抗原
See all Ube2t 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-UBE2T Antibody,
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
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别名
- UBE2T
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背景
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Target Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination.
Gene Symbol: UBE2T
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基因ID
- 29089
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UniProt
- Q9NPD8
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途径
- Chromatin Binding
抗原
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