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RUNX1 抗体

RUNX1 适用: 人, 小鼠, 大鼠 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6298208
发货至: 中国
  • 抗原 See all RUNX1 抗体
    RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 143
    • 17
    • 2
    • 1
    克隆类型
    • 145
    • 19
    多克隆
    标记
    • 104
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    This RUNX1 antibody is un-conjugated
    应用范围
    请咨询
    原理
    Rabbit Anti-AML1 (Ab-435) Antibody,
    Top Product
    Discover our top product RUNX1 Primary Antibody
  • 限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    2-8°C (short-term), -20°C (long-term)
  • 抗原
    RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
    别名
    AML1 (RUNX1 产品)
    背景

    Target Description: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B- dependent transcriptional activation.

    Gene Symbol: RUNX1

    基因ID
    861
    UniProt
    Q01196
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