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ERI1 抗体

The 兔 多克隆 anti-ERI1 antibody (ABIN6298170) specifically detects ERI1. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6298170
发货至: 中国
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Room 801-803
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Quick Overview for ERI1 抗体 (ABIN6298170)

抗原

See all ERI1 抗体
ERI1 (Exoribonuclease 1 (ERI1))

适用

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  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 57
  • 2

克隆类型

  • 57
  • 2
多克隆

标记

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  • 4
  • 4
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
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This ERI1 antibody is un-conjugated

应用范围

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  • 原理

    Rabbit Anti-ERI1 Antibody,
  • 限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    ERI1 (Exoribonuclease 1 (ERI1))

    别名

    ERI1

    背景

    Target Description: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication- dependent histone pre-mRNAs.

    Gene Symbol: ERI1

    基因ID

    90459

    UniProt

    Q8IV48
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