ARHGEF1 抗体
Quick Overview for ARHGEF1 抗体 (ABIN6298119)
抗原
See all ARHGEF1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-ARHGEF1 Antibody,
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))
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别名
- ARHGEF1
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背景
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Target Description: Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2- induced RhoA activation.
Gene Symbol: ARHGEF1
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基因ID
- 9138
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UniProt
- Q92888
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途径
- Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
抗原
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