IGHM 抗体
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- 抗原 See all IGHM products
- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IGHM antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 原理
- Mouse anti-Human IgM Antibody [IHC only]
- 特异性
- Cytoplasm, cell surface and secreted
- 纯化方法
- The Mu heavy chain of human Ig was used as the immunogen for the Anti-IgM antibody.
- 免疫原
- The Mu heavy chain of human Ig was used as the immunogen for the Anti-IgM antibody.
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- 应用备注
- Prediluted format : incubate for 30 min at RT (2)
- 限制
- 仅限研究用
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- 缓冲液
- Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- 抗原
- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
- 别名
- Immunoglobulin heavy constant mu (IGHM 产品)
- 别名
- AI326478 antibody, Igh-6 antibody, Igh-M antibody, Igh6 antibody, Igm antibody, muH antibody, ighm1 antibody, wu:fj14a08 antibody, zgc:101769 antibody, AGM1 antibody, MU antibody, VH antibody, immunoglobulin heavy constant mu antibody, Ighm antibody, ighm antibody, IGHM antibody
- 背景
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Target Description: Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Gene Symbol: IGHM
- 基因ID
- 3507
- UniProt
- P01871
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