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PTH 抗体

The 小鼠 单克隆 anti-PTH antibody (ABIN6297723) specifically detects PTH in IHC, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN6297723
发货至: 中国
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Quick Overview for PTH 抗体 (ABIN6297723)

抗原

See all PTH 抗体
PTH (Parathyroid Hormone (PTH))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PTH antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human Parathyroid Hormone Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic and secreted

    纯化方法

    Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH was used as the immunogen for the Parathyroid Hormone antibody.

    免疫原

    Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH was used as the immunogen for the Parathyroid Hormone antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    PTH (Parathyroid Hormone (PTH))

    别名

    Parathyroid hormone

    物质类

    Hormone

    背景

    Target Description: Epitope of this mAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

    Gene Symbol: PTH

    基因ID

    5741

    UniProt

    P01270

    途径

    cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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