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PTH 抗体

PTH 适用: 人 IHC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297722
发货至: 中国
  • 抗原 See all PTH 抗体
    PTH (Parathyroid Hormone (PTH))
    适用
    • 166
    • 9
    • 9
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 102
    • 74
    • 15
    • 2
    小鼠
    克隆类型
    • 101
    • 90
    单克隆
    标记
    • 123
    • 20
    • 13
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTH antibody is un-conjugated
    应用范围
    • 68
    • 63
    • 57
    • 52
    • 45
    • 31
    • 22
    • 16
    • 14
    • 10
    • 8
    • 8
    • 6
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    • 1
    • 1
    Immunohistochemistry (IHC)
    原理
    Mouse anti-Human Parathyroid Hormone Antibody [IHC only]
    特异性
    Cytoplasmic and secreted
    纯化方法
    Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH was used as the immunogen for the Parathyroid Hormone antibody.
    免疫原
    Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH was used as the immunogen for the Parathyroid Hormone antibody.
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    Discover our top product PTH Primary Antibody
  • 应用备注
    Prediluted format : incubate for 30 min at RT (2)
    限制
    仅限研究用
  • 缓冲液
    Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    PTH (Parathyroid Hormone (PTH))
    别名
    Parathyroid hormone (PTH 产品)
    别名
    PTH1 antibody, Pthp antibody, PTH-(1-84) antibody, Pth1 antibody, Pthr1 antibody, PTH antibody, parathyroid hormone antibody, parathyroid hormone S homeolog antibody, PTH antibody, Pth antibody, pth.S antibody
    物质类
    Hormone
    背景

    Target Description: Epitope of this mAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

    Gene Symbol: PTH

    基因ID
    5741
    UniProt
    P01270
    途径
    cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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