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CD43 抗体

SPN 适用: 人 IHC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297681
发货至: 中国
  • 抗原 See all CD43 (SPN) 抗体
    CD43 (SPN) (Sialophorin (SPN))
    适用
    • 154
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    宿主
    • 96
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    小鼠
    克隆类型
    • 85
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    单克隆
    标记
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    This CD43 antibody is un-conjugated
    应用范围
    • 103
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    Immunohistochemistry (IHC)
    原理
    Mouse anti-Human CD43 Antibody [IHC only]
    特异性
    Cell surface
    纯化方法
    Stimulated human leukocytes were used as the immunogen for the CD43 antibody.
    免疫原
    Stimulated human leukocytes were used as the immunogen for the CD43 antibody.
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    Discover our top product SPN Primary Antibody
  • 应用备注
    Prediluted format : incubate for 30 min at RT (2)
    限制
    仅限研究用
  • 缓冲液
    Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    CD43 (SPN) (Sialophorin (SPN))
    别名
    Leukosialin (SPN 产品)
    别名
    CD43 antibody, GALGP antibody, GPL115 antibody, LSN antibody, A630014B01Rik antibody, Cd43 antibody, Galgp antibody, Ly-48 antibody, Ly48 antibody, Lsn antibody, Lsn1 antibody, gpL115 antibody, sialophorin antibody, SPN antibody, Spn antibody
    背景

    Target Description: It recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop III). 70-90 % of T-cell lymphomas and from 22-37 % of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

    Gene Symbol: SPN///CD43

    基因ID
    6693
    UniProt
    P16150
    途径
    Regulation of Leukocyte Mediated Immunity
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