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ICAM-3/CD50 抗体

ICAM3 适用: 人 FACS, IF, IHC, Func 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297675
发货至: 中国
  • 抗原 See all ICAM-3/CD50 (ICAM3) 抗体
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    适用
    • 112
    • 3
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    宿主
    • 68
    • 43
    • 1
    小鼠
    克隆类型
    • 72
    • 40
    单克隆
    标记
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    This ICAM-3/CD50 antibody is un-conjugated
    应用范围
    • 62
    • 49
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    • 34
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Functional Studies (Func)
    原理
    Mouse anti-Human ICAM-3 Antibody [Sodium Azide Free]
    特异性
    Cell surface
    纯化方法
    Stimulated human leukocytes were used as the immunogen for the anti-ICAM-3 antibody.
    免疫原
    Stimulated human leukocytes were used as the immunogen for the anti-ICAM-3 antibody.
    Top Product
    Discover our top product ICAM3 Primary Antibody
  • 应用备注
    Functional Activity: Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (Order SAF formulation)
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    别名
    Intercellular adhesion molecule 3 (ICAM3 产品)
    别名
    CD50 antibody, CDW50 antibody, ICAM-R antibody, ICAM-3 antibody, ICAM3 antibody, intercellular adhesion molecule 3 antibody, ICAM3 antibody, Icam3 antibody
    背景

    Target Description: Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This mAb is excellent for staining of formalin/paraffin tissues.

    Gene Symbol: ICAM3

    基因ID
    3385
    UniProt
    P32942
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