ICAM-3/CD50 抗体
Quick Overview for ICAM-3/CD50 抗体 (ABIN6297675)
抗原
See all ICAM-3/CD50 (ICAM3) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human ICAM-3 Antibody [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- Stimulated human leukocytes were used as the immunogen for the anti-ICAM-3 antibody.
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免疫原
- Stimulated human leukocytes were used as the immunogen for the anti-ICAM-3 antibody.
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应用备注
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Functional Activity: Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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别名
- Intercellular adhesion molecule 3
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背景
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Target Description: Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This mAb is excellent for staining of formalin/paraffin tissues.
Gene Symbol: ICAM3
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基因ID
- 3385
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UniProt
- P32942
抗原
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