电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ANO1 抗体

ANO1 适用: 人 IF, FACS, IHC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297579
发货至: 中国
  • 抗原 See all ANO1 抗体
    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
    适用
    • 128
    • 31
    • 29
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    宿主
    • 82
    • 50
    小鼠
    克隆类型
    • 68
    • 64
    单克隆
    标记
    • 58
    • 13
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ANO1 antibody is un-conjugated
    应用范围
    • 63
    • 52
    • 43
    • 37
    • 35
    • 20
    • 18
    • 13
    • 13
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC)
    原理
    Mouse anti-Human TMEM16A Antibody (DOG1) [Sodium Azide Free]
    特异性
    Cell Surface and Cytoplasmic
    纯化方法
    Recombinant human TMEM16A/DOG1 protein was used as the immunogen for this TMEM16A antibody.
    免疫原
    Recombinant human TMEM16A/DOG1 protein was used as the immunogen for this TMEM16A antibody.
    Top Product
    Discover our top product ANO1 Primary Antibody
  • 应用备注
    FACS: 0.5-1 μg/million cells
    IF: 0.5-1 μg/mL
    IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS ( pH 7.4), BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
    别名
    Anoctamin-1 (ANO1 产品)
    别名
    DOG1 antibody, ORAOV2 antibody, TAOS2 antibody, TMEM16A antibody, Tmem16a antibody, anoctamin 1 antibody, anoctamin 1, calcium activated chloride channel antibody, Ano1 antibody, ANO1 antibody
    背景

    Target Description: Expression of TMEM16A (DOG1) protein is elevated in the gastrointestinal stromal tumors (GIST 's), c-kit signaling-driven mesenchymal tumors of the GI tract. It is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for TMEM16A has been reported in 97.8 percent of scorable GIST 's, including all c-kit negative GIST 's. Overexpression has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha (PDGFR alpha) mutants that fail to express c-kit antigen. The overall sensitivity of TMEM16A and c-kit in GIST 's is nearly identical: 94.4 % vs. 94.7 %.

    Gene Symbol: ANO1///DOG1///ORAOV2///TAOS2///TMEM16A

    基因ID
    55107
    UniProt
    Q5XXA6
You are here:
客服