SUMO3 抗体
Quick Overview for SUMO3 抗体 (ABIN6297570)
抗原
See all SUMO3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human SUMO2/3 Antibody [Sodium Azide Free]
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特异性
- Predominantly nuclear with some cytoplasmic
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纯化方法
- Recombinant human SUMO2 protein was used as the immunogen for this SUMO2/3 antibody.
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免疫原
- Recombinant human SUMO2 protein was used as the immunogen for this SUMO2/3 antibody.
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anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-103) antibody
SUMO3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-103) antibodySUMO3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-92) antibodySUMO3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-103) antibodySUMO3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B9 unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-92) antibodySUMO3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (N-Term) antibodySUMO3 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 豚鼠, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (C-Term) antibodySUMO3 适用: 人, 小鼠 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-103) antibodySUMO3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 6-55) antibodySUMO3 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 小鸡, Pig, 豚鼠, 马, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 38-64) antibodySUMO3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))
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别名
- Small ubiquitin-related modifier 3
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背景
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Target Description: This antibody reacts with both SUMO2 and SUMO3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursors that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets for a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO1/2/3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO1 utilizes Ubc9 for conjugation to several targets, which include MDM2, p53, PML and RanGap1. SUMO2/3 contribute to a greater percentage of protein modification than does SUMO1 and they can form polymeric chains. In addition, SUMO3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer 's disease.
Gene Symbol: SUMO3///SMT3A///SMT3H1
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基因ID
- 6613
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UniProt
- P55854
抗原
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