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SELPLG 抗体

This 小鼠 单克隆 antibody specifically detects SELPLG in FACS, IHC 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN6297562
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SELPLG 抗体 (ABIN6297562)

抗原

See all SELPLG 抗体
SELPLG (Selectin P Ligand (SELPLG))

适用

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  • 44
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宿主

  • 78
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  • 9
小鼠

克隆类型

  • 69
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  • 3
单克隆

标记

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This SELPLG antibody is un-conjugated

应用范围

  • 74
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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    Mouse anti-Human CD162 Antibody / P selectin glycoprotein ligand 1 / PSGL-1 [Sodium Azide Free]

    特异性

    Cell surface

    纯化方法

    Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.

    免疫原

    Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    SELPLG (Selectin P Ligand (SELPLG))

    别名

    P-selectin glycoprotein ligand 1

    背景

    Target Description: P selectin glycoprotein ligand 1 (PSGL-1), also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.

    Gene Symbol: SELPLG

    基因ID

    6404

    UniProt

    Q14242
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