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PAX6 抗体

This anti-PAX6 antibody is a 小鼠 单克隆 antibody detecting PAX6 in WB, IF 和 FACS. Suitable for 人, 小鼠, 大鼠 和 小鸡.
产品编号 ABIN6297257
发货至: 中国

Quick Overview for PAX6 抗体 (ABIN6297257)

抗原

See all PAX6 抗体
PAX6 (Paired Box 6 (PAX6))

适用

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人, 小鼠, 大鼠, 小鸡

宿主

  • 94
  • 43
  • 1
小鼠

克隆类型

  • 80
  • 57
单克隆

标记

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  • 1
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This PAX6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human/Mouse/Rat/Chicken PAX6 Antibody [Sodium Azide Free]

    特异性

    Nuclear

    纯化方法

    Recombinant human PAX6 protein was used as the immunogen for this antibody.

    免疫原

    Recombinant human PAX6 protein was used as the immunogen for this antibody.
  • 应用备注

    FACS: 0.5-1 μg/million cells
    IF: 0.5-1 μg/mL
    WB: 0.5-1 μg/mL,

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS ( pH 7.4), BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    PAX6 (Paired Box 6 (PAX6))

    别名

    Paired box protein Pax-6

    背景

    Target Description: PAX genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the PAX6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters ' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The PAX6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human PAX6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.

    Gene Symbol: PAX6///AN2

    基因ID

    5080

    UniProt

    P26367

    途径

    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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