ATP7A 抗体
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北京 101111
Quick Overview for ATP7A 抗体 (ABIN629724)
抗原
See all ATP7A 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- ATP7 A antibody was raised using a synthetic peptide corresponding to a region with amino acids MKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVKSSEGSQQRSPSYQ
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应用备注
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WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ATP0 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
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别名
- ATP7A
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背景
- The ATP7A gene encodes the Menkes copper-translocating P-type ATPase, a ubiquitous protein that regulates the absorption of copper in the gastrointestinal tract. Inside cells, this protein has a dual function: it delivers copper to cuproenzymes in the Golgi compartment and effluxes excess copper. The trafficking mechanism and catalytic activity combine to facilitate absorption and intercellular transport of copper. Menkes disease, a systemic copper deficiency disorder, is caused by mutations in the ATP7A gene.
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分子量
- 30 kDa (MW of target protein)
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途径
- Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
抗原
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