AMPD3 抗体
Quick Overview for AMPD3 抗体 (ABIN6296990)
抗原
See all AMPD3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Mouse anti-Human AMPD3 Antibody [Sodium Azide Free]
-
特异性
- Cytoplasmic, membrane
-
纯化方法
- Recombinant full-length human protein was used as the immunogen for the AMPD3 antibody.
-
免疫原
- Recombinant full-length human protein was used as the immunogen for the AMPD3 antibody.
-
-
-
-
应用备注
-
Flow Cytometry: 1-2 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL,Immunocytochemistry: 1-2 μg/mL for 30 min at RT
Immunohistology (FFPE): 2-4 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
-
-
-
缓冲液
- In 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
-
- AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))
-
别名
- AMP deaminase 3
-
背景
-
Target Description: It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This mAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This mAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
Gene Symbol: AMPD3
-
基因ID
- 272
-
UniProt
- Q01432
抗原
-