IFNA1 抗体
Quick Overview for IFNA1 抗体 (ABIN6296890)
抗原
See all IFNA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human Interferon alpha Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic, extracellular (secreted)
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纯化方法
- Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.
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免疫原
- Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.
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应用备注
- ELISA: order BSA/azide-free format for coating
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限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- IFNA1 (Interferon, alpha 1 (IFNA1))
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别名
- Interferon alpha-1/13
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背景
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Target Description: This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
Gene Symbol: IFNA1///IFNA13
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UniProt
- P01562
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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