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S100B 抗体

The 小鼠 单克隆 anti-S100B antibody (ABIN6296805) specifically detects S100B in WB, IHC, IF 和 FACS. The antibody is reactive with 人, 大鼠, 小鼠 和 Cow samples.
产品编号 ABIN6296805
发货至: 中国
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北京 101111
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Quick Overview for S100B 抗体 (ABIN6296805)

抗原

See all S100B 抗体
S100B (S100 Calcium Binding Protein B (S100B))

适用

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人, 大鼠, 小鼠, Cow

宿主

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小鼠

克隆类型

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单克隆

标记

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This S100B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human/Mouse/Rat/Cow S100B Antibody Cocktail [Sodium Azide Free]

    特异性

    Cytoplasmic, nuclear

    纯化方法

    Purified bovine brain S100 protein (4C4.9) and recombinant full-length human protein (S100B/1012) were used as the immunogen for the S100 antibody cocktail.

    免疫原

    Purified bovine brain S100 protein (4C4.9) and recombinant full-length human protein (S100B/1012) were used as the immunogen for the S100 antibody cocktail.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Western blot: 0.5-1 μg/mL
    Immunohistology (FFPE): 0.25-0.5 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    S100B (S100 Calcium Binding Protein B (S100B))

    别名

    Protein S100-B

    背景

    Target Description: S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.

    Gene Symbol: S100B

    基因ID

    6285

    UniProt

    P04271

    途径

    Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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