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Histone H1 抗体

This anti-Histone H1 antibody is a 小鼠 单克隆 antibody detecting Histone H1 in IHC, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6296761
发货至: 中国

Quick Overview for Histone H1 抗体 (ABIN6296761)

抗原

See all Histone H1 (H1F0) 抗体
Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

适用

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人, 小鼠, 大鼠

宿主

  • 37
  • 5
小鼠

克隆类型

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  • 15
单克隆

标记

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This Histone H1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human/Mouse/Rat Histone H1 Antibody [Sodium Azide Free]

    特异性

    Nuclear

    纯化方法

    Nuclei of human leukemia biopsy cells were used as the immunogen for the anti-Histone H1 antibody.

    免疫原

    Nuclei of human leukemia biopsy cells were used as the immunogen for the anti-Histone H1 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

    别名

    Histone H1.0

    背景

    Target Description: Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer, formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80 % of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

    Gene Symbol: H1F0///H1FV

    基因ID

    3005

    UniProt

    P07305
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