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IDH3A 抗体

This anti-IDH3A antibody is a 兔 多克隆 antibody detecting IDH3A in WB 和 IHC. Suitable for 人, 大鼠, 小鼠 和 犬.
产品编号 ABIN629675
发货至: 中国

Quick Overview for IDH3A 抗体 (ABIN629675)

抗原

See all IDH3A 抗体
IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

适用

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人, 大鼠, 小鼠, 犬

宿主

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克隆类型

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多克隆

标记

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This IDH3A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Purified

    免疫原

    IDH3 A antibody was raised using a synthetic peptide corresponding to a region with amino acids MKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLK
  • 应用备注

    WB: 1.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    IDH3A Blocking Peptide, catalog no. 33R-6142, is also available for use as a blocking control in assays to test for specificity of this IDH3A antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IDH0 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

    别名

    IDH3A

    背景

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit.

    分子量

    40 kDa (MW of target protein)
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