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CD38 抗体 (Biotin)

This anti-CD38 antibody is a 小鼠 单克隆 antibody detecting CD38 in ELISA. Suitable for 人.
产品编号 ABIN6296644
发货至: 中国

Quick Overview for CD38 抗体 (Biotin) (ABIN6296644)

抗原

See all CD38 抗体
CD38

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD38 antibody is conjugated to Biotin

应用范围

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ELISA

克隆位点

1G8-G9-H11
  • 原理

    Mouse anti CD38 (1G8-G9-H11) [+Biotin] Antibody,

    免疫原

    Immunogen was recombinant Human CD38 that derived from E.coli. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.

    亚型

    IgG2b
  • 应用备注

    ELISA (recommended work dilution= 1:500,000)

    限制

    仅限研究用
  • 溶解方式

    Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution. Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    -20°C
  • 抗原

    CD38

    别名

    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

    背景

    Target Description: CD38  (cluster of differentiation  38), also known as  cyclic ADP ribose hydrolase  is a  glycoprotein found on the surface of many immune cells (white blood cells), including  CD4+,  CD8+,  B lymphocytes  andnatural killer cells. CD38 also functions in  cell adhesion,  signal transduction  and  calcium signaling. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. Diseases associated with CD38 include B Cell Prolymphocytic Leukemia and Richter's Syndrome. Among its related pathways are Hematopoietic cell lineage and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. GO annotations related to this gene include transferase activity and hydrolase activity, acting on glycosyl bonds. An important paralog of this gene is BST1.

    Gene Symbol: CD38

    基因ID

    952

    UniProt

    P28907
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