CD38 抗体 (Biotin)
Quick Overview for CD38 抗体 (Biotin) (ABIN6296644)
抗原
See all CD38 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti CD38 (1G8-G9-H11) [+Biotin] Antibody,
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免疫原
- Immunogen was recombinant Human CD38 that derived from E.coli. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.
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亚型
- IgG2b
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应用备注
- ELISA (recommended work dilution= 1:500,000)
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限制
- 仅限研究用
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溶解方式
- Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution. Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- -20°C
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- CD38
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别名
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
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背景
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Target Description: CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes andnatural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. Diseases associated with CD38 include B Cell Prolymphocytic Leukemia and Richter's Syndrome. Among its related pathways are Hematopoietic cell lineage and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. GO annotations related to this gene include transferase activity and hydrolase activity, acting on glycosyl bonds. An important paralog of this gene is BST1.
Gene Symbol: CD38
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基因ID
- 952
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UniProt
- P28907
抗原
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