CD2 抗体
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北京 101111
Quick Overview for CD2 抗体 (ABIN6296614)
抗原
See all CD2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Cat CD2 Antibody [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- Human thymocytes were used as the immunogen for the CD2 antibody.
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免疫原
- Human thymocytes were used as the immunogen for the CD2 antibody.
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应用备注
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Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: 1-2 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD2
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别名
- T-cell surface antigen CD2
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背景
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Target Description: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
Gene Symbol: CD2///SRBC
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基因ID
- 914
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UniProt
- P06729
抗原
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