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S100A9 抗体

This anti-S100A9 antibody is a 小鼠 单克隆 antibody detecting S100A9 in WB, IHC, IF 和 FACS. Suitable for 人 和 大鼠.
产品编号 ABIN6296494
发货至: 中国

Quick Overview for S100A9 抗体 (ABIN6296494)

抗原

See all S100A9 抗体
S100A9 (S100 Calcium Binding Protein A9 (S100A9))

适用

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人, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This S100A9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human/Rat S100A9 Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic, extracellular (secreted) and cell surface

    纯化方法

    Human peripheral blood monocyte components were used as the immunogen for the S100A9 antibody.

    免疫原

    Human peripheral blood monocyte components were used as the immunogen for the S100A9 antibody.
  • 应用备注

    Western blot: 1-2 μg/mL
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    S100A9 (S100 Calcium Binding Protein A9 (S100A9))

    别名

    Protein S100-A9

    背景

    Target Description: This mAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. It plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

    Gene Symbol: S100A9///CAGB///CFAG///MRP14

    基因ID

    6280

    UniProt

    P06702

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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