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Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体

This anti- antibody is a 兔多克隆 antibody detecting in WB 和 IHC. Suitable for 人, 大鼠, 小鼠和犬.

DUT antibody used at 2. (Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体)

DUT antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Myocardial cells (arrows) in Human Heart. (Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体)

DUT antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. (Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体)

3 images

产品编号 ABIN629626

发货至: 中国

Quick Overview for Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体 (ABIN629626)

抗原

See all Deoxyuridine Triphosphatase (DUT) 抗体

Deoxyuridine Triphosphatase (DUT)

适用

80
32
17
2
2
1
1
1
1
1
1

人, 大鼠, 小鼠, 犬

宿主

兔

克隆类型

多克隆

标记

30
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1

非结合性

应用范围

63
26
26
22
18
15
8
6
4
1
1

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product DUT Primary Antibody

抗原表位
15

15

9

7

3

3

2

2

1

1

1

1

1

1

1

1
C-Term

特异性

DUT antibody was raised against the C terminal of DUT

纯化方法

Purified

免疫原

DUT antibody was raised using the C terminal of DUT corresponding to a region with amino acids NFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTERGSGGFGSTGKN
anti-Deoxyuridine Triphosphatase (DUT) (AA 68-164) antibody
DUT 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1C9 unconjugated

anti-Deoxyuridine Triphosphatase (DUT) antibody
DUT 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (AA 89-252) antibody
DUT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (Internal Region) antibody
Verified DUT 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (AA 151-252) antibody
DUT 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) antibody
DUT 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (AA 1-252) antibody
DUT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibody
DUT 适用: 人, 大鼠, 小鼠, 犬, Bat, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (N-Term) antibody
DUT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (N-Term) antibody
DUT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 2.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator.

说明

DUT Blocking Peptide, (ABIN5613272), is also available for use as a blocking control in assays to test for specificity of this DUT antibody

限制

仅限研究用
状态

Lyophilized

溶解方式

Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DUT antibody in PBS

浓度

Lot specific

缓冲液

PBS

注意事项

Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

储存条件

4 °C/-20 °C

储存方法

Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
抗原

Deoxyuridine Triphosphatase (DUT)

别名

DUT

背景

DUT is an essential enzyme of nucleotide metabolism. This protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death.

分子量

19 kDa (MW of target protein)

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