Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体
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Quick Overview for Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体 (ABIN629626)
抗原
See all Deoxyuridine Triphosphatase (DUT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- DUT antibody was raised against the C terminal of DUT
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纯化方法
- Purified
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免疫原
- DUT antibody was raised using the C terminal of DUT corresponding to a region with amino acids NFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTERGSGGFGSTGKN
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anti-Deoxyuridine Triphosphatase (DUT) antibody
KD Validated DUT 适用: 人 WB, IF (p), ICC, FACS 宿主: 兔 Monoclonal 23GB5240 unconjugated Recombinant Antibody
anti-Deoxyuridine Triphosphatase (DUT) (AA 68-164) antibodyDUT 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 89-252) antibodyDUT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) antibodyDUT 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (Internal Region) antibodyVerified DUT 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibodyDUT 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 151-252) antibodyDUT 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) antibodyDUT 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 1-252) antibodyDUT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibodyDUT 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 2.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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DUT Blocking Peptide, (ABIN5613272), is also available for use as a blocking control in assays to test for specificity of this DUT antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DUT antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Deoxyuridine Triphosphatase (DUT)
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别名
- DUT
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背景
- DUT is an essential enzyme of nucleotide metabolism. This protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death.
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分子量
- 19 kDa (MW of target protein)
抗原
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