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CNN1 抗体

This 小鼠 单克隆 antibody specifically detects CNN1 in FACS, IHC 和 IF. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN6296236
发货至: 中国
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Quick Overview for CNN1 抗体 (ABIN6296236)

抗原

See all CNN1 抗体
CNN1 (Calponin 1 (CNN1))

适用

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人, 大鼠

宿主

  • 72
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  • 2
小鼠

克隆类型

  • 59
  • 53
单克隆

标记

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  • 1
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This CNN1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    Mouse anti-Human/Rat Calponin Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    Crude human uterus extract was used as the immunogen for the Calponin antibody.

    免疫原

    Crude human uterus extract was used as the immunogen for the Calponin antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CNN1 (Calponin 1 (CNN1))

    别名

    Calponin-1

    背景

    Target Description: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this mAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

    Gene Symbol: CNN1

    基因ID

    1264

    UniProt

    P51911
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